NGN Clinical Case Studies

330 Unfolding NGN Case Studies for the NCLEX

Each case presents a real patient scenario with 6–7 linked clinical-judgment questions — exactly the NCSBN April 2026 NGN format. Bow-tie, matrix, cloze, trend, and extended-response items across all 6 CJMM layers.

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Endocrine cases

22 cases shown
Endocrine7 questions

Diabetic Ketoacidosis (DKA) Management

The nurse is planning care for this patient with DKA.

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Endocrine11 questions

Pediatric Diabetic Ketoacidosis: Recognition and Safe Management

The nurse is triaging Liam upon arrival. Which findings from the assessment are consistent with the diagnosis of moderate diabetic ketoacidosis (DKA) in a pediatric patient?

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Endocrine6 questions

Type 2 Diabetes: Chronic Management, Hypoglycemia, and Complication Prevention

The nurse completes the initial assessment of Mrs. Holloway during check-in. Select ALL findings that indicate hypoglycemia requiring immediate treatment.

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Endocrine8 questions

Pediatric Diabetic Ketoacidosis (DKA)

Elijah is a 9-year-old male (28 kg) with no PMH. Mother reports 2 days of vomiting, polydipsia, polyuria, and now confusion. T 37.8°C, HR 138, RR 30 (deep, sighing), BP 88/54, SpO2 98%, glucose 684 mg/dL, capillary refill 3.5 sec, dry mucous membranes, fruity breath, confused. ABG: pH 7.09, PaCO2 18

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Endocrine6 questions

Pediatric DKA with Cerebral Edema: CJMM Clinical Progression

CASE 12 — Maya Johnson, 11-year-old, newly diagnosed Type 1 DM. Parents noted 3 weeks of polyuria, polydipsia, weight loss. Today: lethargic, vomiting, Kussmaul respirations (deep, rapid). Glucose 648 mg/dL, pH 7.12, HCO3 8, pCO2 18, Na+ 128 (corrected ~137), K+ 5.8 mEq/L. Large urinary ketones. Wei

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Endocrine6 questions

Severe Alcohol Withdrawal with Delirium Tremens: CJMM Clinical Progression

CASE 15 — Mr. Patrick Sullivan, 52-year-old male. PMH: Alcohol use disorder (daily drinking since age 28; approximately 750 mL vodka/day). Admitted for elective hernia repair 36 hours ago. Surgical team did NOT obtain alcohol history. Surgery uneventful. NPO post-op. PRESENTING at 36 hours post-op:

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Endocrine6 questions

Necrotizing Pancreatitis: Hypertriglyceridemia and Alcohol Use

Mr. Roberto Vasquez is a 46-year-old male admitted for severe necrotizing pancreatitis from hypertriglyceridemia (TG 4,820 mg/dL) and chronic alcohol use. He is on day 5 of treatment. TG have decreased to 820 mg/dL with insulin infusion. Pain is controlled. He was started on nasojejunal tube feeds o

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Endocrine6 questions

Severe Hyperkalemia Emergency with ECG Changes

Darnell Washington is a 58-year-old male with CKD 3b (baseline creatinine 2.8, baseline K+ 4.8), T2DM, and HTN admitted for an infected diabetic foot ulcer. Home medications continued: lisinopril 20 mg daily, spironolactone 25 mg daily, insulin glargine. Current IV antibiotic: TMP-SMX for MRSA foot

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Endocrine6 questions

Diabetic Foot Osteomyelitis with Critical Limb Ischemia and Charcot Foot

Gabriel Santos is a 67-year-old male with 22-year history of type 2 diabetes (HbA1c 10.8%), PAD (ABI 0.58 bilaterally), and peripheral neuropathy (absent 10-gram monofilament bilateral feet). He presents to the wound care clinic because his wife noticed his left foot is 'red and swollen' and he feel

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Endocrine6 questions

Limb-Threatening Diabetic Foot: Wagner Classification and Vascular Emergency

[NURSE'S NOTES] Patient: Gabriel Santos, 67-year-old male Setting: Wound Care Clinic → Medical-Surgical Unit Clinical Context: Gabriel Santos is a 67-year-old male with a 22-year history of type 2 diabetes (HbA1c 10.8%), peripheral artery disease (ABI 0.58 bilaterally), and peripheral neuropathy con

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Endocrine6 questions

Severe Alcohol Withdrawal: Wernicke Encephalopathy and Refeeding Risk

[NURSE'S NOTES] Patient: Florence Nakamura, 54-year-old female Setting: Medical-Surgical Unit Clinical Context: Florence Nakamura is a 54-year-old female with a 12-year history of alcohol use disorder (AUD) — drinks a fifth of vodka daily, last drink approximately 36 hours ago. She is malnourished (

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Endocrine6 questions

Hyperosmolar Hyperglycemic State: Fluid Resuscitation and Insulin Management

The nurse reviews Mr. Okafor's admission data: blood glucose 740 mg/dL, Na 148 mEq/L, serum osmolality 328 mOsm/kg, BUN 32, creatinine 1.6, no urine ketones, BP 98/60 mmHg, HR 118 bpm, GCS 13, dry mucous membranes, poor skin turgor. He has T2DM, HTN, and CKD stage 2. Which findings are PRIORITY conc

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Endocrine6 questions

Pediatric DKA: Cerebral Edema Risk and Insulin-Potassium Safety

Jordan Kim, 14-year-old male, is brought to the pediatric ED by his parents who report a 2-week history of polyuria, polydipsia, and 8-pound weight loss. Today he vomited twice and is breathing 'strangely.' Assessment: T 37.2C, HR 118, BP 98/62, RR 28 (deep, sighing respirations), SpO2 97%, fruity o

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Endocrine6 questions

Severe Acute Pancreatitis — LR Resuscitation, Infected Necrosis, CIWA

Mr. Torres, 38M heavy drinker with SAP, shock, Ranson criteria. Aggressive LR, thiamine before glucose, CIWA monitoring, infected necrosis management.

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Endocrine6 questions

New-Onset Type 2 Diabetes — Metformin, DSMES, Foot Care

Mrs. Mills, 58F with HbA1c 8.9%, polyuria/polydipsia. Metformin initiation, complication screening, hypoglycemia management, foot care.

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Endocrine6 questions

Severe Hyperkalemia — Calcium Gluconate, Insulin+D50, Emergent Dialysis

Mr. Obi, 52M CKD with K+ 7.8, ECG changes. Sequential treatment, hypoglycemia monitoring.

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Endocrine6 questions

Pediatric T1DM — Basal-Bolus Insulin, Sick-Day Rules, Glucagon

Sophie, 11F newly diagnosed T1DM. Insulin technique, hypoglycemia management, school safety, sick-day rules.

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Endocrine6 questions

New-Onset Type 2 Diabetes in a Middle-Aged Adult: Diagnosis, Education, and Self-Management

Mr. David Torres, a 52-year-old male, presents to his primary care clinic for a routine physical. He reports increased thirst, frequent urination (app...

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Endocrine6 questions

Ischemic Stroke: Acute Recognition, tPA Eligibility, and Rehabilitation Nursing

Mrs. Patricia Okafor, a 71-year-old female with a history of atrial fibrillation (on apixaban — last dose yesterday morning), hypertension, and hyperlipidemia, is brought to the ED by her husband at 9:15 AM. He reports she was 'perfectly fine' at breakfast at 8:45 AM and suddenly developed slurred speech and could not lift her right arm while clearing the table. Time last known well (LKW): 8:45 AM. Current time: 9:20 AM — symptom onset 35 minutes ago. Neurological exam: right facial droop, right upper extremity (RUE) weakness (4-/5 strength), slurred speech (dysarthria), mild right leg weakness. NIHSS (National Institutes of Health Stroke Scale) score: 9. Vital signs: BP 188/104 mmHg, HR 76 bpm (irregular), RR 16/min, Temp 36.9°C, SpO₂ 97% on room air. Fingerstick glucose: 142 mg/dL. CT head (non-contrast): no hemorrhage, no early ischemic changes. Platelet count: 218,000. INR: 1.1. The stroke team is activated.

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Endocrine6 questions

Chronic Kidney Disease: Monitoring, Dietary Management, and Complications

Mr. Roberto Sanchez, a 64-year-old male with a 15-year history of type 2 diabetes and hypertension, is seen in the nephrology clinic for management of stage 3b chronic kidney disease (CKD). His most recent labs: eGFR 32 mL/min/1.73m², serum creatinine 2.4 mg/dL, BUN 38 mg/dL, potassium 5.4 mEq/L, sodium 138 mEq/L, bicarbonate 19 mEq/L, phosphorus 5.8 mg/dL, calcium 8.4 mg/dL, hemoglobin 10.1 g/dL, hematocrit 30%, albumin 3.4 g/dL, urine albumin-to-creatinine ratio (UACR) 380 mg/g (severely elevated). Current medications: lisinopril 10 mg daily, amlodipine 5 mg daily, metformin 1000 mg BID, atorvastatin 40 mg daily. BP today: 146/88 mmHg. He reports fatigue, mild ankle edema bilaterally, and decreased appetite. He asks, 'How serious is my kidney disease and what can I slow it down?'

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Endocrine6 questions

Medication Safety: High-Alert Medications, the Rights of Administration, and Error Prevention

A busy medical-surgical unit has a nurse preceptor (RN, 8 years experience) orienting a new graduate nurse (NGN) on day 3 of orientation. The unit cares for patients with a variety of medical diagnoses. The following scenarios occur during the shift. Patient 1: Mr. Henry Bloom, 78-year-old male, prescribed: insulin glargine (Lantus) 20 units SQ at bedtime AND insulin lispro (Humalog) sliding scale AC meals. Patient 2: Mrs. Clara Nguyen, 65-year-old female, prescribed: heparin 5,000 units SQ q8h for DVT prophylaxis. Patient 3: Mr. Tyler Ross, 52-year-old male, prescribed: metoprolol succinate (Toprol-XL) 50 mg PO daily AND metoprolol tartrate (Lopressor) 25 mg PO q6h PRN for HR >100 bpm. The preceptor uses each patient encounter to teach high-alert medication safety principles.

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Endocrine6 questions

Dka Insulin Omission

Complete the Bow-Tie clinical reasoning diagram for a 19-year-old male with Type 1 diabetes who ran out of insulin 2 days ago and presents with severe hyperglycemia, acidosis, and altered breathing pattern. Select the condition most consistent with the presentation, TWO priority nursing actions, and TWO parameters to monitor.

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